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Description
Patent-pending XOSM technology

In this issue of Diabetologia, Kang et al (DOI: 10.1007/s00125-012-2776-x ) provide evidence that in addition to glucotoxicity, lipotoxicity also affects incretin receptor expression and signalling in insulin-secreting cells and isolated islets
New research reveals that elevated GLP-1 and its receptor contribute to brain inflammation and nausea in NMOSD, offering a new target for treatment strategies.

Saxenda is taken once daily whilst Compounded Semaglutide, Ozempic and Wegovy is to be taken weekly

Higher-risk patients may hold once-weekly injectable dosing for 1 week to minimize delayed gastric emptying and aspiration risk
GLP-1
