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2024 February 29(March 2024)

Although some studies have found an association between PPI use and increased intestinal permeability, animal research models are not adequate

Gastroparesis has no cure, but your provider may recommend treatment with medications, lifestyle changes, diet, and sometimes surgery

TRIUMPH-4, the first completed Phase 3 trial, showed 28.7% average body weight loss at 68 weeks on retatrutide 12mg versus 2.1% on placebo, as reported by Eli Lilly in December 2025 (peer-reviewed publication pending)

Taking Rybelsus with a meal may help reduce the risk of gastrointestinal side effects, such as nausea, vomiting, or diarrhea, which are common when starting the medication
