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It suppresses release of glucagon , a hormone that signals the liver to send the glucose it contains into circulation

doi: 10.1016/j.cbi.2018.01.004

Yesterday, Novo Nordisk announced that a new weight loss shot it hoped would rival Eli Lillys injectable actually underperformed in a head-to-head trial, tanking Novos stock

Medicare Part D Coverage of Antiobesity Medications - Challenges and Uncertainty Ahead

But it almost certainly reduces the gastrointestinal rebound effects that some researchers report after abrupt cessation, including paradoxical increases in appetite, changes in bowel habits, and blood sugar fluctuations