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The FDA flagged marketing claims suggesting that compounded GLP-1s shared the same safety and efficacy profiles as their branded counterparts, noting that such labeling can mislead consumers and violate the Food, Drug, and Cosmetic Act

The OASIS 1 and 2 trials compared the therapeutic efficacy and clinical safety profile of once-daily oral semaglutide 50 mg versus placebo on overweight and obese participants without T2DM and both with and withoutT2DM, respectively

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