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It exerts various physiological effects by acting on the area postrema in the brainstem
181,182 Poor sleep is associated with insulin resistance, increased hunger, and weight gain, which might reduce some benefits of GLP-1s

With Wegovy specifically, animal reproduction studies suggest potential risks to the fetus from semaglutide exposure

Although current clinical studies have demonstrated a correlation between PPIs and cholelithiasis, the specific effect of PPI-induced changes in the intestinal flora on cholelithiasis remains unclear

doi: 10.1016/S0021-9258(18)68261-4 141 GkeRLarsenPJMikkelsenJDSheikhSP

Healthy fats Fat gets a bad rap, but not all types of dietary fat are the same
