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Obesity and metabolic disorders are on the rise globally

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The impact of GLP-1 medications on fertility and during pregnancy raises important considerations for individuals trying to conceive.

Danish drugmaker Novo Nordisk is launching its once-daily Wegovy pill in the United States on Monday, offering 1.5 milligram (mg) and four mg doses at US$149 per month for self-paying patients in an intensely competitive weight-loss drug market

While a number of mechanisms including vascular, myocardial, renal, and central nervous system pathways have been suggested in animal studies, these mechanistic pathways have not been sufficiently detailed in humans and it is unclear if the same pathways are operational