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The primary physiologically native incretins include glucagon-like-peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) [88]

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This may change if demand increases and synthesis becomes feasible, but for now, access is limited to approved markets

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Multiple GLP-1R agonists have entered into clinical trials, with some, such as semaglutide, progressing to approval

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an intestinal immune barrier made up of the intestinal lymphatic system

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