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All had normal brain imaging (apart from radiological signs of raised ICP), and this included magnetic resonance venography or computed tomography venography to exclude venous sinus thrombosis

The SURMOUNT-1 trial for tirzepatide showed average weight loss of 15% of starting body weight at 36 weeks (roughly 8.5 months)

Remodeling Plaque towards Stability Plaques that are vulnerable to rupture have a distinctive pathological phenotype, comprising extensive inflammatory infiltration and a necrotic core with an overlying thin fibrous cap [154]