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Unfortunately, Genfit was disappointed to report in May 2020 that the study did not meet its key primary endpoints

Safety profile : Whilst lower doses might theoretically reduce the incidence of dose-dependent adverse effects such as nausea and vomiting, this has not been systematically studied, and the overall risk-benefit ratio remains unknown
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The most frequently reported side effects during retatrutide initiation are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal discomfort
