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Protein kinase C and fatty acid transport protein 4 (FATP4) [144] play an important role in the increase of GLP-1 secretion and improvement in glycemic tolerance caused by oleic acid (OA), both in vivo and in vitro [145]

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Studies have found that (Val 8 )GLP-1 protects synapses from the detrimental effects of A fragments on synaptic plasticity formation (171173)

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Additionally, a small retrospective series described 17 patients with perianal fistulizing CD treated with a GLP-1RA, reporting improvements in fistula drainage and pain scores

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