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[77] discovered that tirzepatide therapy drastically reduced the expression of the apoptotic marker BAX/Bcl2 ratio while up regulating markers such as MAP2, GAP-43, and AGBL4, all of which are important for neuronal plasticity and differentiation

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At the top dose, nausea affected 42.4% of people and vomiting affected 25.3%, with diarrhoea and constipation also more common than on placebo

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Magnesium citrate is a widely available mineral supplement supporting numerous bodily functions, whilst Mounjaro (tirzepatide) is an MHRA-licensed prescription medication for type 2 diabetes treatment