semaglutide or tirzepatide less side effects than People in online communities are sharing their experiences with the Switching from Semaglutide to Tirzepatide:

If your weight loss is too rapid or profound, you may sacrifice muscle mass (sarcopenia), which can lead to a marked decrease in appetite and difficulty consuming enough protein

Analysis found fewer major complications overall with tirzepatide, including stroke and all causes of death A Cleveland Clinic analysis has found that tirzepatide, a medication that activates both GLP1 and GIP hormone receptors, was associated with a lower risk of serious heart and kidney complications compared with the GLP1 medication dulaglutide in adults with type 2 diabetes and cardiovascular disease

But in the real world, consistently getting near your daily intake target is what really matters

Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

Now comes the latest headline: a large randomized trial testing tirzepatide (Zepbound) for Long COVID

If these technologies mature to the point where a 39-amino acid peptide can be reliably delivered orally with clinically meaningful bioavailability, an actual oral tirzepatide pill becomes possible