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10.3389/fendo.2018.00584 [DOI] [PMC free article] [PubMed] [Google Scholar] RamosLobo, A

Both the 2016 consensus statement of the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) on management of type 2 diabetes and the 2016 American Diabetes Association (ADA) standards recommend adding on GLP-1 RAs to patients not meeting treatment goals with basal insulin

Specifically, while the GLP-1 peptide sequence is identical across mammalian species, the human GLP-1 receptor differs from that of the rat GLP-1 receptor at 42 amino acid residues