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Or it can mean moving on to another medication altogether as part of a step therapy approach

Sulfur burps on GLP-1 are unpleasant but common, particularly in the early weeks of treatment

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Progressive proximal muscle weakness (affecting shoulders and hips more than hands and feet) may indicate an inflammatory myopathy or other serious neuromuscular condition that requires investigation beyond simply attributing symptoms to GLP-1 therapy

For an oral antibiotic like amoxicillin, this is typically not a major concern for its overall effectiveness, but its a factor your healthcare provider should be aware of