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Semaglutide is the active ingredient in GLP-1 receptor agonist medications that reduce the feeling of hunger

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Further treatments include mandibular advancement devices, positional therapy, hypoglossal nerve stimulation, and surgical procedures such as adenotonsillectomy or orofacial surgery

This is generally safe under medical supervision, but self-escalating to this dose without provider guidance is risky

Several preclinical studies suggest that GLP-1 receptor agonists increase populations of short-chain fatty acidproducing bacteria