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Finally, we considered only membrane-bound GLP1R immunohistochemistry as truly specific, a basic request for the immunohistochemical characterization of all GPCRs, 28 to which family the GLP1Rs also belong

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The primary risks include cardiovascular effects (phentermine can increase heart rate and blood pressure), compounded gastrointestinal adverse effects (nausea, vomiting), excessive appetite suppression leading to nutritional deficiencies, and potential mental health effects such as anxiety or mood changes

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