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Comparative estimate of glucose-lowering therapies on risk of incident pneumonia and severe sepsis: an analysis of real-world cohort data

This could happen if the treatment and control groups are not comparable- for example if doctors prescribed GLP-1s vs another diabetes medication for systematic reasons such as the health profile of the patient

Albiglutide (Tanzeum [also available as Eperzan], GlaxoSmithKline) is a fusion of two repeats of GLP-1 and rDNA-derived human albumin

Dose Range: 510 mg daily (standard)

Cagrilintide is engineered to reproduce this receptor-level activity while carrying structural modifications that confer an extended half-life, improving its stability for laboratory investigation

Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, but it remains unlicensed in the UK and is only available within regulated clinical trials