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Monitor appetite, food intake, body weight, and any gastrointestinal symptoms during this period

Having pre-portioned, healthy meals ready reduces decision fatigue when appetite is low

SNc, substantia nigra, compact part

Other AEs reported with SGLT2i use include osmotic diuresis-related events and volume depletion-related hypotension, the latter of which tends to be more common in older adults, people with an eGFR of 3060 mL/min/1.73 m 2 , and in those taking loop diuretics [4]

This is a top-down approach to weight management because the drug acts directly on the central nervous system, essentially telling the brain to quiet down its hunger signals before they ever reach the conscious decision-making level

We did not have the corresponding benefit on cognition that we had hoped for, he said