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The sub-study estimates put the lean-mass share of total weight lost somewhere in the region of 25 to 40 percent, depending on the population, the measurement method, and how the analysis is done

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Cardiometabolic complications are inside the indication, not adjacent to it

This indicates that there are mechanisms that go well beyond just weight loss or glucose lowering, she says

10 Semaglutide has demonstrated significant cardiovascular benefits, particularly in reducing the risk of major adverse cardiovascular events, such as heart attacks and strokes

Yes, the SURMOUNT-1 clinical trial specifically focused on adults with obesity or overweight who did not have diabetes