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In the search for novel treatment strategies for alcohol use disorder (AUD), glucagonlike peptide1 (GLP1) receptor agonists (GLP1RAs) approved for treating Type 2 diabetes and obesity have caught much attention

However, the coexistence of micro and macrovascular disease is associated with the highest cardiovascular risks which highlights the importance that pharmacological treatment of type 2 diabetes mellitus provides not only glycemic control, but also cardiovascular safety

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Among the marketed large molecule injectable GLP-1 agonists, semaglutide, apart from weight-loss, is being studied for kidney disease and tirzepatide (a dual GLP-1 and GIP receptor agonist) is being evaluated for sleep apnea in Ph 3 clinical trials
