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What we know from the best large-scale data, including the American Gut Project , is that overall diet patternsespecially eating a wide variety of plant-based foodshave a far greater impact on gut microbiome health than any single ingredient

Side effects and unknown long-term outcomes Because of the relative newness of GLP-1 medications, long-term effects beyond a few years of use are unknown

Chan School of Public Health, said in the article

What Are the BMI and Health Requirements to Qualify for GLP-1 Treatment

The analysis of cardiovascular outcomes trials (CVOTs) revealed consistent benefits

10.1016/j.soard.2016.11.004 105