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I was surprised that results were still significant when we compared the nonage-matched groups because that includes younger patients who presumably have had less lifetime exposure to smoke, he said

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TLR9 antagonist administration before e-cigarette vapor exposure not only mitigated TLR9 upregulation in atherosclerotic plaques but also suppressed the increase in plasma levels of inflammatory cytokines and accumulation of lipids and macrophages in the plaques

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[1] [18] Pro 3: Vaping can lower health care costs