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Effects of smoking cessation with nicotine replacement therapy on vascular endothelial function, arterial stiffness, and inflammation response in healthy smokers

Such studies have found that the minor tobacco alkaloids can partially substitute for nicotine in behavioural tests but have lower potency than nicotine itself

These proceedings were concluded in 1998 with the Tobacco Master Settlement Agreement between four US majors, Philip Morris, RJ Reynolds, Brown & Williamsons (a subsidiary of BAT), and Lorillard, and 46 US states, with the tobacco companies paying compensation of 206 billion dollars

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