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"Something that concerns us are claims about the product being discreet," adds Meghan Moran, an associate professor in the Department of Health, Behavior, and Society at the Johns Hopkins Bloomberg School of Public Health who is working with Spindle to research nicotine pouches

We recommend that all people who smoke tobacco cigarettes be encouraged to stop and offered 1 or more recommended smoking cessation interventions (strong recommendation, high certainty)

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The translocator protein (TSPO) is used as a neuro-inflammatory marker as its expression is upregulated in reactive glial cells during CNS pathologies