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Mahapatra, S., Kamath, R., Shetty, B

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The pipe may also gurgle and go out more frequently

60 Enhanced levels of CCL2 (also known as monocyte chemotactic protein-1, and an important CCR2 ligand) were observed in the lung of cigarette smoke-exposed mice and in patients with COPD

(1) uninfected macrophages express anti-inflammatory responses, including polarization of CD206 + M2 macrophages and increased expression of IL10, whereas (2) infected macrophages show inflammatory responses, including differentiation to M1 macrophages and increased expression of iNOS, TNF-, and IL6