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For example, mixing psilocybin with alcohol or stimulants like cocaine can compound risks, including panic attacks, psychosis, and accidents during intoxication

It is also relevant for cigarette taxes, which lower both smoking prevalence and smoking intensity

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Pickworth, Does marijuana blunt smoking contribute to nicotine exposure?: Preliminary product testing of nicotine content in wrappers of cigars commonly used for blunt smoking, Drug and Alcohol Dependence, Volume 168, 2016, Pages 119-122, ISSN 0376-8716, (