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E-cigarette aerosol can contain: highly addictive nicotine that can harm brain development ultrafine toxic particles that can interfere with the growth and work of the lungs and increase the risk of heart disease, lung cancer, and asthma attacks harmful heavy metals such as lead, tin, and nickel volatile organic compounds that can cause long-term health effects including cancer

NRT products like mints, lozenges, gum, and patches are labeled in mg per piece

Guidelines to an international treaty on tobacco control recommend that the more than 180 member countries ban or restrict cigarette flavorings

12 countries classified them as therapeutic products and 14 countries classified them as consumer products.[24] The taxation of e-cigarettes or liquids was reported in very few countries

[9] A 2016 analysis of data from the 19992013 National Youth Tobacco Surveys suggests that the ban reduced adolescent cigarette useboth probability of smoking a cigarette and number of cigarettes used by smokersalthough there was an increase in adolescent use of menthols, smokeless tobacco, flavored cigars, and pipes, suggesting substitution towards the remaining legal flavored tobacco products