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In their analyses of data from 4,850 elderly participants free of overt CHD, heart failure, and significant valvular disease in the ARIC study, Nadruz and colleagues (2016) found that, after adjusting for potential confounders, current smokers had a greater left-ventricular mass index and left-ventricular mass/volume ratio, a higher prevalence of left-ventricular hypertrophy, and worse diastolic function than never smokers

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Destaillats takes pains to note that the results do not mean that e-cigarettes are safe to use at lower temperatures

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