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Reducing nicotine levels in cigarettes could complement these strategies and bring us one step closer to a society free of tobacco-related disease and death. Cigarette smoking remains the leading cause of preventable disease and death in the United States, responsible for an estimated 480,000 deaths each year

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These efforts not only sustained the downward trend in prevalence but also helped to cut down on the intensity of smoking among a significant portion of smokers

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One Swedish study of women aged 30 to 50 years found an increased age-adjusted risk of sICH in former smokers (RR, 1.6) compared to non-smokers, although this study had a limited number of subjects [44]