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These toxic and carcinogenic ingredients induce tumorigenesis in the GI tract through several possible mechanisms, including the activation of nicotinic acetylcholine receptors (nAChRs), the formation of DNA adducts, stimulation of tumor angiogenesis, the involvement of immune response and others (Fig
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"Evidence review of e-cigarettes and heated tobacco products 2018" (PDF)

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Smoking kills There are three million smokers in Australia

Retrieved January 2, 2026
