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In light of its superior safety profile, Health Canada mandated a label change in 2013 advising thorough consideration of NRT before prescribing either varenicline or bupropion to any smoker, further stating that in many cases, nicotine replacement therapy should be tried before prescribing varenicline or bupropion [9], emphasizing the need to optimize the effectiveness of this first-line medication

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J Pharmacol Exp Ther 1999;289:154552

Although there's minimal risk, avoiding sharing drinking straws or other items is still recommended

The plug has an integral fuse which is essential for protection of any wandering lead or attached equipment