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[326] A play entitled Rosalind: A Question of Life was written by Deborah Gearing to mark the work of Franklin, and was first performed on 1 November 2005 at the Birmingham Repertory Theatre, [327] and published by Oberon Books in 2006

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The reduction of FMD caused by smoking was used as a marker for endothelial dysfunction (ED), thus demonstrating for the first time a clinically relevant link between tobacco smoke and vascular dysfunction

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Global production [edit] Trends [edit] Production of tobacco leaf increased by 40% between 1971, during which 4.2 million tons of leaf were produced, and 1997, during which 5.9 million tons of leaf were produced