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Psychopharmacology 164(2):177187 Teneggi V, Tiffany ST, Squassante L, Milleri S, Ziviani L, Bye A (2005) Effect of sustained-release (SR) bupropion on craving and withdrawal in smokers deprived of cigarettes for 72 h

Nicotine-specific human evidence is less developed, though animal studies consistently show reduced nicotine-seeking

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We recommend that all people who smoke tobacco cigarettes be encouraged to stop and be offered 1 or more of the recommended smoking cessation interventions (strong recommendation, high certainty)

After two years of growth, consumption of cigarettes containing tobacco decreased by -20% to 1,942B units in 2024