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The problem isnt a lack of awareness among some youth, but rather naivety

SIRT7 can cause doxorubicin resistance by interacting and inducing deacetylation of p53, and thereby reducing affinity for the NOXA promoter and its transcription 164
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doi:10.1136/tc.12.4.349

Therefore, UVR exposure results in a p53-driven cell cycle arrest by transactivating genes involved in G1 and G2 phases
