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For decades, Big Tobacco publicly denied what it internally knew to be true

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Oral cytisine has a shorter half-life (4.8 vs 17 hours) and treatment course (3.5 vs 12 weeks) than varenicline 110

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RNA isolation and real-time PCR Total RNA from cells exposed to extracts for 48 h was extracted using TRIzol reagent (Invitrogen) and quantified using a nano-drop followed by Reverse Transcriptase PCR using random primers per manufacturers recommendations

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