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The latter is often required when combining smaller, local cohorts
Those first records we listened to all had 808 drums
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They vary in how they respond to treatment
Blank samples were averaged by batch before blank correction, and values below the laboratory LOD were imputed with a value of one-half the detection limit before averaging
(2004 update on www.ctsu.ox.ac.uk) 21.Zaridze D, Peto R
