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[9] Tobacco was introduced elsewhere in continental Europe more easily

Disease prevention and social change, the state, society, and public health in the United States, France, Great Britain and Canada (Russell Sage Foundation, 2007)

Tobacco became one of the main crops harvested on the large colonial plantations and, as demand for the plant grew in Europe, the Spanish overlords worked the natives harder

Such legislation failed to meet with the approval of the home government and in 1641 tobacco averaged about two pence per pound

the column temperature program was 60250 C (2 C min 1 ), 250290 C (5 C min 1 ), and held at 290 C for 20 min

Notably, chlorogenic acid and neochlorogenic acid were found to be present in relatively high concentrations, collectively constituting 67.98% of the total compounds identified (Supplementary Table S1)