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Enter tobacco harm reduction (THR), the idea that some smokers can wean themselves off cigarettesby far the most dangerous form of tobacco consumptionby switching to alternative nicotine or tobacco products
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Furthermore, the accuracy of the findings may be compromised by the introduction of biases, such as recall bias or social desirability bias, as a result of the reliance on self-reported data
a 2012 good-quality systematic review found the abstinence rate of participants who received combination pharmacotherapy and intensive behavioral counseling was 14.5%, at 6 months or more, compared with 8% among control participants who received usual care, self-help materials, or brief advice on quitting (which was less intensive than the counseling or support given to the intervention groups) (RR, 1.82
