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King James I of England and James VI of Scotland, the same person, published his famous treatise A Counterblaste to Tobacco in 1604, a vehement denunciation that described smoking as a custome loathsome to the eye, hatefull to the Nose, harmfull to the braine, dangerous to the Lungs. The plant that would transform colonial America was not the indigenous tobacco of eastern North America, which was milder and less commercially appealing, but Nicotiana tabacum , the species found in South America