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Description
MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway

Post-translational modifications and activation of p53 by genotoxic stresses
Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS, Hainaut P
National studies have determined that when smoking is started in teenage years and continues into adulthood, the typical smokers life span is approximately 810 years less than the non-smoker

"Johansson (Female Celebrity Smoking List)"

Olivier M, Hollstein M, Hainaut P