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It typically reaches 4 to 6 feet tall with broad leaves that mature over the growing season, ready for harvest late summer to early fall in zones 7 and above

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This was especially true in the century between 1880 and 1980, when several major tobacco companies formed the base of North Carolinas economy

Our result showed relatively higher BEN increase in prefrontal cortex, lateral striatum, visual cortex, and motor area, which is consistent with the fact that nicotine dependence has the strongest impact on attention, decision making, reward, and action/motion function that are subserved by those brain regions

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