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Sensitive periods of substance abuse: early risk for the transition to dependence

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In group 2, cigarette smoking yielded an acute increase in mitral Aa (+12.1%, p = 0.0026), tricuspid Sa (+9.8%, p = 0.012) and TAPSE (+7.9%, p = 0.017), and a decrease in the mitral Ea/Aa ratio (-8.5%, p = 0.0084)

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The human genome also contains highly complex and specialized repair mechanisms to correct the ROS-induced damage to critical macromolecules [23, 51, 52, 86, 126, 183]

J Med Internet Res
