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Description
Cigarettes are engineered for frequent, deep inhalation, with paper and reconstituted tobacco burned along with the filler
The accumulation of misfolded proteins triggers the unfolded protein response (UPR), a protective mechanism to restore protein homeostasis and mitigate cellular damage
September 7, 2014
Progressively, throughout the day, nicotine's systemic threshold for pleasure and arousal and that for withdrawal symptoms rises, creating a recurring demand for cigarettes
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Jha, P., Mony, P., Moore, J
