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doi:10.1146/annurev.pharmtox.45.120403.095930

How to Quit Smoking: Every Treatment Ranked by Actual Evidence (Part 4) From varenicline to hypnosis to cold turkey a pulmonologist tiers every option by what the research actually shows, not what the marketing says

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[23] [24] The company sold nearly 130 million nicotine pouch cans in the US in 2020 [25] and nearly 198 million in 2021

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Smoking remains a major contributor of all-cause mortality in Europe 5,6 , with a marked disparity in rates of tobacco use between Western and Central and Eastern Europe 7,8