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Briefly, the studies that were extracted represented several types of study design (for example, cohort and casecontrol studies), measured exposure in several different ways and varied in their choice of reference categories (where some compared current smokers with never smokers, whereas others compared current smokers with nonsmokers or former smokers)

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This is the least amount of tobacco that I have ever raised on this farm, said Burrier, who traces his familys tobacco-growing heritage back a century

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Less serious side effects include severe acne and changes in sex characteristics, like shrinking of the testicles in men and growth of facial hair in women