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Just one cigarette could be enough to turn you into a daily smoker, according to a new study
doi: 10.1093/ntr/ntq208
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Any new products that were not on the market on 2/15/2007 must submit a Premarket Tobacco Application that is wildly expensive
As mentioned before, in vitro models are very well adapted for mechanistic studies
One study (Lewis-Esquerre et al., 2005) evaluated the TLFB method with adolescent smokers, and found it produced less digit bias than global reports, and that averaged consumption figures from TLFB correlated reasonably well with biochemical measures of smoking
