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Smoking-caused health care costs: $2.51 billion per year Smoking-caused losses in productivity: $1.54 billion per year Minnesota tobacco laws Tobacco taxes Minnesota is ranked 7th in the U.S

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Dev Psychopathol (2016) 28(1):5572
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The age- and sex-specific risks of a tobacco-attributable death were estimated by comparing the risk of death for smokers and non-smokers

Furthermore, future clinical trials should address multi-morbidity smokers such as those with chronic obstructive pulmonary disease and cardiovascular/cerebrovascular diseases, who have an urgent need for effective treatment to quit smoking