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Likewise, interventions that increase serotonin have shown promising effects on LES function, motility, and reflux (15)

Smoking has been strongly linked to negative clinical outcomes in asthma, including suboptimal asthma control [14], accelerated decline in lung function [20, 37, 38], increased exacerbations [39], reduced response to inhaled corticosteroids [40], greater health care utilization and a higher prevalence of chronic bronchitis

WIN also showed a significant increase in the percentage of cells in the G1 phase and a decrease in the percentage of cells in the S phase suggesting that WIN cause cell cycle arrest in prostate cancer cells, although a previous study reported that there was no significant difference in the distribution of PC3 cells treated with endocannabinoids across the cell cycle phases compared with the control non-treated group of PC3 cells (Singh et al

PAHs like benzo[a]pyrene (B[a]P), radionuclides and alfatoxins have been classified as potent carcinogens by the International Agency for Research on Cancer (IARC) 6,18,19