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Several factors can influence how long a product stays fresh, including: Moisture content Packaging quality Exposure to heat or sunlight Frequency of opening the can Portion products with sealed packaging generally retain freshness longer than products exposed to frequent air contact

This supports hypothesis 1

Available from: Wei Xia, William Ho Cheung Li, Yuan Hui Luo, Ting Na Liang, Laurie Long Kwan Ho, Ankie Tan Cheung, Peige Song, The association between heated tobacco product use and cigarette cessation outcomes among youth smokers: A prospective cohort study, Journal of Substance Abuse Treatment, Volume 132, 2022, 108599, ISSN 0740-5472, Sun T, Anandan A, Lim CCW, East K, Xu SS, Quah ACK, et al

We produce approximately 6 trillion cigarettes every year, generating over 1.2 million tons of cigarette butt waste

PMID 27288378

Effective Date: October 24, 2024 Recommendations and Topics Scope Background Epidemology Screening and Brief Intervention Pharmacological Management of TUD Special Populations Vaping Use Controversies in Care Appendices References Scope This guideline provides evidence-based recommendations for primary care practitioners on managing tobacco use disorder (TUD)