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Conclusions: These changes suggest a phenotypic shift from concentric hypertrophy to eccentric hypertrophy in nicotine-exposed, hemodynamically-stressed mice which could drive HF pathogenesis

Controlling the false discovery rate: a practical and powerful approach to multiple testing

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Advice should be clear and strong, for example, As your physician and someone who cares about you and your health, I would encourage you to stop smoking because it is the most important thing you can do to protect your health. This advice works best when delivered in a non-judgmental tone and is personalized where possible, such as, linking the advice to the reason for the patient's visit

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Beneficiaries also have the option to switch to a Medicare Advantage (a.k.a., Medicare Part C) plan that will typically cover all traditional Part A and Part B services as well as (sometimes) Part D prescription drug coverage